G6PD deficiency - Treatment in Ayurveda

Treatment of G6PD deficiency in Ayurveda | Treatment of G6PD deficiency through alternative medicine | Treatment of G6PD deficiency through Herbs 

Initially we shall like to share with you the details with regard G6PD deficiency, so patient too gains in knowledge and then he can very well understand the treatment protocols and other dietary recommendations as well.

G6PD is an enzyme called glucose-6-phosphate-dehydrogenase. An insufficient amount of this enzyme is termed G6PD deficiency.

Though the disease is rarely fatal, it causes a spectrum of complaints and chronic breakdown of red blood cells. G6PD is a genetic, X-linked, metabolic disorder, passed on from mother to mostly the male child (females are usually healthy carriers of the gene defect). G6PD is an enzyme that keeps the red blood cells (RBCs) healthy and plays an important role in oxidizing processes. A deficiency can lead to sudden destruction of red blood cells. G6PD plays an important role in the production of a chemical – glutathione. This chemical antioxidant is essential for maintaining the integrity of the cell walls of the RBCs. Hemoglobin is the oxygen carrying protein in blood. It is a major component of all red blood cells and gives them their red color. This protein picks up oxygen from the lungs, carries it throughout the body and delivers it to all your cells. In addition, hemoglobin also picks up some of the carbon dioxide produced by the cells and transports it to the lungs from where it is exhaled out. Cells need Oxygen for their basic functions and to keep them alive. Hence, without enough red blood cells to transport oxygen to your cells and carbon dioxide away from your cells, it is like literally suffocating every tissue and organ system in the body.

Cause of Concern : 

When glutathione levels are very low, the hemoglobin in the RBCs are unable to bind with oxygen. This breaks down the cell wall, spilling out all its contents. Deficiency of G6PD can lead to hemolytic anemia because of oxidative damage to RBCs

Most forms of G6PD are mild and do not have any symptoms. Symptoms develop when people are either exposed to certain foods or drugs (fava beans; sulpha-drugs and particularly those drugs having ‘-quine’ at the end of their names), or when the person is severely ill, or when exposed to noxious substances.

Symptoms develop when rapid breakdown of RBCs occurs and it can be varied from patient to patient basis - 

Appearing very pale
Sudden rise in body temperature
Rapid heart beats
Shortness of breath
Pain in the back or abdomen
Urine appears very dark, red, red-brown, brownish or tea colored
Yellow coloring of the eyes and skin (jaundice)
Spleen may be enlarged

The symptoms usually disappear when the offending food or drug is stopped and thus are rarely fatal. Awareness and knowing well about one's own illness is always the key. 

Nearly half the blood flowing in our veins and arteries consists of red blood cells which carry oxygen to the tissues. Approximately 100 million new blood cells are formed daily in the bone marrow. The raw materials required in the production of these cells are iron, proteins, and vitamins, especially folic acid and B12. Of these, iron and proteins are essential in building up the red coloring matter called haemoglobin. A red cell has a lifespan of approximately 120 days and is then destroyed and replaced. Each person should have about 15 gm of hemoglobin per 100 ml of blood, and a blood count of approximately five million red cells per millimetre of blood.

In Ayurveda terminology, its basically referred as Pandu Roga. In Sanskrit pandu word means pale or swetapeet varna. So the disease in which, due to rakta alpata (deficiency of blood) whole body becomes pale (skin, nails, eyes) is called panduroga.. It is pitta dominant Tridoshaja vyadhi and thus the Medicinal herbs which shall be prescribed for such patients are aimed towards normalization in all the three "Doshas" of body. 

Ayurvedic System of Medicine is one of the best remedies to control this harmful physical disorder that affects in adverse manners. Prepared with the Organic Medicinal Herbs, the ayurvedic medicines are aimed at the well being of the patients that suffer from G6PD Deficiency or other disorders. No side effects are involved in these medications. 

Treatment through Medicinal Herbs is aimed towards correction of Physiology at "dosha" level and longevity in the normalization of "Raktaj Dhatu" has to be achieved. Once its done, certainly the symptoms shall reduce much lesser in terms of intensity and the quality of life of concerned patient can be enhanced. 

According ayurveda when rasa (lymph) is mixed with "ranjaka pitta"(haemoglobin) it forms Rakta dhatu or blood. 

Following are the explanation in "Ras Shatra" - "Raktam varna prasaadanam mamsa pushtim jeevayathicha"

Rakta dhatu enhances tone and complexion of skin. It strengthens and nourishes "mamsa dhatu" (Muscles). The whole physiology of body is dependent on this tissue. Rakta strengthens the body andkeeps it healthy. It increases life span and keeps the person active.

Starting with Rakta Dhatu – its main role is Jeevana – giving life.  Because it is the vehicle for Prana – carries it through the body.  And through medicinal herbs, its longevity in health aspects has to be ensured and thats the prime treatment modality of such types of patients. 

The Herbal Formulation is "Swarna Raktaj Kshaya Rasayana" and  its in the form of tablets. It has to be taken as 2 tablets in morning and 2 in evening on empty stomach with lukewarm water. Meals can be taken 30 minutes afterwards. The herbal medication has to be taken for a complete duration of minimum 8 months for the first year of treatment process. Thereafter a gap of 12 months shall be given. From then on, every year the medication has to be taken for only 3-4 months and its to be continued as such for 5 years in succession. By then, majority of such patients recover towards good probability and an improved quality of ife, as the LONGEVITY OF A HEALTHY CELL IS MUCH ENHANCED AND BOUTS OF SIGNS ARE EITHER NIL OR MUCH LESSER IN TERMS OF INTENSITY.